Pathogenesis of Gall Stones in the Gall Bladder
The stones in the gall bladder are mostly widespread in the countries of the North West.
The surveys in the United States have showed a pervasiveness rate of the gall stones in every 20 out of a hundred women and about 8 out of a hundred men, all at an average age of about forty. The surveys have also been showing that the United States is the place where the cases of the gall stones patients have been on a surge.
The gall stones are called as the Cholelithiasis. Theses gall stones, if defined structurally are crystalline in shape and are formed by the concretion of the normal or sometimes the abnormal constituents of the bile. The gall stones can be classically classified into three main groups. These may be the cholesterol and the mixed stones which have a dominance rate of about eighty percent. There are the pigments stones which are found to be about the remaining twenty percent.
Now regarding the pathology of these gall stones the mixed and the cholesterol stones contain more than seventy percent of the cholesterol monohydrate with the addition of the calcium salts, with the addition of bile pigments that is bilirubin and biliverdin, bile acids, fatty acids, phospholipids and even a substantial amount of proteins.
The pigment stones on the other hand are the once which cannot be said to have been originated from the bile pigments as the name may suggests. Though they are named as the pigment stones they are the mainly formed by the calcium bilirubinate that is a salt from the pigments of bile and not directly the bilirubin and biliverdin.
These varieties of the gall stones are said to be having all the constituents of the gall stones of that of the cholesterol and mixed variety but all in trace amounts and that the presence of cholesterol also but the prevalence is only about ten percent.